They are white blood cells that contain granules of chemicals such as histamines. Its important to follow your vets instructions and stick to the schedule they provide for the most effective treatment. Mast cell tumours in the skin have extremely varied appearances that it can sometimes be mistaken as a fatty lump or noncancerous skin lesions. Options include a second surgery or radiation therapy. There are three grades of mast cell tumors , and this is very predictive of how the tumor behaves clinically. They account for 16% to 21% of all skin tumors in dogs. They are the same cells that cause the itchy, red bump you get after a mosquito bite or the more serious reactions that occur in people allergic to peanuts or shellfish. Diagnosing visceral mast cell tumors can be harder to define. . You are responsible for making this appointment with the front desk: 1052 William Moore Drive However, we often forget that both internal and external factors are going to affect our dogs lives in the future, with the grimmest perspective being the one of cancer. Any lump or bump you find on your dog that persists for over a week should be examined by a vet. Discuss treatment methods with your veterinarian and veterinary oncologist. If you notice that your dog has pale gums or they have collapsed, you will want to call your vet and get them to the emergency room for treatment as quickly as you can. Yes, antihistamines like Benadryl can be useful to block histamine production in the treatment and management of mast cell tumors. Its important to follow your vets instructions and stick to the schedule they provide for the most effective treatment. When we adopted Bindi in December of 2014 she had a small bump on the bridge of her nose. Once the cancer progresses, dogs may show some of the following symptoms: Weight loss. They are common in dogs, accounting for approximately 20% of all skin tumors. Other dogs will develop a rapidly growing tumor that changes dramatically in a few short days to weeks. Unfortunately, they can also form on the lining of the lips, salivary glands, conjunctiva, and in some rare cases, on the spine. This includes antihistamines (diphenhydramine/Benadryl), antacids (famotidine/Pepcid or omeprazole/ Prilosec), and corticosteroids (prednisone). Mast cells stain purple, while their contents of histamine stain dark. The cutaneous form is more prevalent, and is . In many cases, both internal and external tumors may be present and their development can come in several stages. These represent 14-21% of all skin tumors diagnosed in dogs. Recovery from anesthesia and brief hospitalization are required with any surgical procedure and risks include those associated with any form of anesthesia and surgery. There is some speculation that mast cell tumors may develop secondary to skin disease/inflammation, but this is not always the case. Let us dive deeper into this subject and work out the best medical and nutritional plan against this disease! or vomiting, which might be an indication that it is time to end the . Thankfully, mast cell tumors are one of the more treatable types of cancer in dogs. General information. The earlier the tumor is caught, the higher the survival rate. Vomiting, diarrhea, lethargy, reclusive behavior, hair loss, increased urination and increased or decreased thirst can appear during the early stages of cancer. Tumors can be irritating and dogs will scratch, lick, or bite the mass and surrounding skin. Mast cell tumors are the most common type of skin cancer found in dogs and account for approximately 14 to 21% of all diagnosed skin tumors in these animals. These samples may be obtained by aspiration or fine needle biopsy, and will help your vet decide on the best course of treatment. While in the past centuries, the cancer diagnosis was more or less the kiss of death for many dogs, nowadays, with the help of scientific developments, improved detection techniques, and the application of holistic therapies our canine companions have a chance at enjoying a healthy life once again. The release of chemicals from granules leads to allergic reactions. The majority of pets tolerate chemotherapy very well and are able to enjoy their normal lifestyle. One important thing to know about diagnosing mast cell tumors is that they have been called the great pretenders in that they may mimic or resemble other conditions. Chemotherapy often carries a negative impression, especially with our understanding of chemotherapy in human medicine. 4 MCTs are often seen as solitary lumps or masses in or underneath the skin. Mast cell tumors on the skin cant be diagnosed just by looking at them, because they dont always look the same. It could be a condition called vestibular disease. Mast Cell Cancer. Dogs may also have multiple mast cell tumors at the same time that arose independently. 15 New Thoughts About End Stage Mast Cell Cancer In Dogs Symptoms That Will Turn Your World Upside Down. Mast cells are normal cells found in the body. As we have seen, the direction in which a mast cell tumor can evolve is hard to predict. Specialists prefer radiation therapy when the tumor is not in a suitable location for surgical removal additionally, they can include this treatment form when cancerous cells are left behind after surgical removal. 15 Little Tricks To Achieve The Best Results In End Stage Mast Cell Cancer In Dogs Symptoms. In recent years, as part of an effort to reduce confusion about the best treatment for Grade II tumors, a new system has been introduced to classify mast cell tumors as either high grade or low grade. So how do you know when its time to let your canine companion go? You May Like: Why Is My Dogs Throw Up Orange. What is Mast Cell Cancer? The final reason that chemotherapy would be recommended is if the tumor is in a negative prognostic location . In this treatment option, your vet will provide medicines such as antihistamines and steroids to keep your dog comfortable. As we have seen earlier, todays scientific developments are capable of removing mast cell tumors and restoring your canine friends well-being and happiness. For most tumors, regardless of grade, additional therapy is recommended if the initial surgery was unsuccessful in removing the entire tumor. Why mast cells accumulate into potentially malignant dog tumours is unclear. MCTs are the most common malignant skin tumours in dogs and up to 20% of skin masses in dogs are MCTs. Therefore, tumors can be difficult to detect. The mast cell tumor is located where the skin and mucous membranes connect. What are the final stages of mast cell tumors in dogs? Check your dog regularly and consult your veterinarian straight away if you find any mysterious lumps or nodules. Side effects are associated with the treatment selected and the extent of disease and clinical signs. The key to stopping MCT progression and healing tumors is to deal with the disease at a root level: Tumors need sugar for energy. They are usually found as individual masses but some dogs may present with multiple tumours. Acquiring tumor free surgical margins can be challenging . They can also increase and decrease in size over time. We understand this is a difficult time and we are here to support you and your pet by providing the options and care necessary. Mast cell tumors are most commonly found on the skin but can be felt in the layer under the skin called the cutaneous layer. Lymphoma is most common in middle aged dogs, from 6 to 9 . Boosting your dogs immune system with the proteoglycans and polysaccharides from the mushrooms a nutritional dog immune builder. 5 Explanation On Why End Stage Mast Cell Cancer In Dogs Symptoms Is Important. These tumors are made up of the mast cells that give them their name. For skin tumors, localized redness and irritation is possible. Symptoms include a mass on the gums, bleeding, odor, or difficulty eating. One important thing to know about diagnosing mast cell tumors is that they have been called the great pretenders in that they may mimic or resemble other conditions. Also, getting the tumor to shrink will increase the chance that clean surgical margins can be obtained. In more serious cases, the chemicals can affect the entire body, causing severe gastrointestinal bleeding and even an anaphylactic reaction, which can be fatal if untreated. 10 Things You Probably Didn't Know About End Stage Mast Cell Cancer In Dogs. In cases where its important to know the aggressiveness of the tumor to best manage it, a surgical tissue sample can be beneficial. Others appear as red, ulcerated, bleeding, bruised, and/or swollen growths. Therefore, it is recommended to keep your pet at a healthy weight with a healthy diet and exercise to aid in preventing mast cell tumors in dogs. Mast cell tumor in dog symptoms include: Scratching. Mast cell tumors (MCT) are the most common skin. Stages of Mast cell tumors. Mast cell tumors are a type of cancer that arises from mast cells. Approximately 50% of cutaneous MCTs are found on the trunk and perineal region, approximately 40% on the extremities, and about 10% arise from . These dog skin cancers, which occur in the mast cells of the immune system, are the most common skin tumors in canines. {"@context":"https://schema.org","@type":"FAQPage","mainEntity":[{"@type":"Question","name":"What is the life expectancy of a dog with a mast cell tumor? Weakness. These masses can occur on any part of the body, are very unpredictable, and can vary in appearance. While some dogs will experience a sudden decline in health that warrants a quick decision, others will carry on comfortably in the following months, even years. Dogs who suffer from allergic reactions may be more likely to develop mast cell tumors. If the lymph nodes are very large, they can affect breathing because they are blocking the throat. However, in higher-grade tumors, even without evidence of spread, a combination of surgery and chemotherapy is often recommended. Although there is no telling how these tumors will behave in the future, proper medical treatment, alongside a diet effective at starving off cancer cells, are your dogs best fighting gear against mast cell tumors. Boxers and Boston terriers make up ~ 50% of all cases. The results of these tests will allow veterinarians to develop individualised treatment recommendations for your dog. In lower-grade tumors with no evidence of spread, surgery is likely the best option. During this procedure, a small hypodermic needle is inserted into the mass and a nearly imperceptible amount of tissue is withdrawn. A mast cell tumor a malignant skin tumor that is composed of an abnormal collection of mast cells. Mast cell tumours in dogs are extremely variable in their location, appearance, and growth pattern. In order to remove all of the cancer cells in a mast cell tumour, normal tissue must be removed for 2-3 cm around the site of the edge of the tumour, and into muscle tissue deep to the tumour. This is a cancer where the numbers of mast cells multiply out of control-a classic case of too much of a good thing. The grade reflects the degree to which the malignant mast cells differ from normal, non-malignant mast cells. Any lump or bump on your dog should be looked at by a veterinarian. Since we cant ask our dogs how they are feeling each day, its important to understand the signs of a sick dog. Severe digestive tract symptoms including vomiting, diarrhea and abdominal cramping from stomach ulcers are often the terminal effects of mast cell cancer, marking the end of quality of life. Some may look like raised bumps within, or just below the surface of, the skin. Mast cell tumors are among the most commonly reported canine skin tumors. Growth pattern of mast cell tumours in dogs: Nutrition Strength Immune Support for Dogs Plus Antioxidant, Reishi, Shiitake, Maitake, Turkey Tail Mushrooms for Dogs, with Coenzyme Q10, Nutritional Support for Dogs, 120 Chewable Tablets are a tasty mix of ingredients that may help strengthen your dogs immune system and keep them healthy. Sign up for the best pet advice you can get. They are going to be small and usually there are no symptoms present to tell you there is problem. Although these breeds may have the highest incidence, any dog breed can develop such tumors. Here is a comprehensive list for proper cancer detection in dogs: Despite their unpredictable behavioral patterns, todays scientific progress has developed multiple ways of treating mast cell tumors. It occurs when there is a collection of mast cells in an area. Chat with a veterinary professional in the Wag! They are very invasive and difficult to treat. Lethargy. Decreased appetite and lethargy may also occur. Mast cell tumors are typically diagnosed via a fine-needle aspiration . After about two weeks, your dog should be able to resume normal activity once any stitches have been removed unless your vet tells you otherwise. Mast cell tumors are formed by DNA mutations of mast cells. Mast cell tumors are the most common type of skin tumor found in dogs and the second most common skin tumor in cats. Mast cell tumors are usually located in one spot, however, they can spread to the lymph nodes, blood, liver, spleen, and skin cells. estimated that at the time of diagnosis, ~6% of dogs have tumor cells that spread to the lymph nodes. This disease has a cutaneous form (skin) and a systemic form (internal organs). Mast cell tumors are one of the most common cancers in dogs. Chemotherapy in human medicine is provided with the intent to cure by using very high doses which often result in increased side effects. Located in connective tissue throughout the body, mast cells are white blood cells that are part of the immune system. If your dog is having urinary problems, it's essential that you take your dog to the vet for an examination. Other owners can notice the lumps aggressive forming, and it can grow in a matter of days. Sometimes these lumps can change size, getting larger and smaller with time. Chemotherapy Chemotherapy is used to treat mast cell tumors that have already spread or have a high risk of spreading. Written by Mast cells are actually an important part of a dog's immune system. However, there is a small percentage who have significant side effects with rare cases that require hospitalization. Why ZipZyme is a healthier, more sustainable source of docosahexaenoic acid (DHA) for your dog or cat than fish oil. Mast cells contain granules packed with chemicals including histamine. . In patients with non-surgical MCT, or recurrent MCT that has failed to respond to other chemotherapies, targeted therapy becomes a much more appealing option. The prognosis may be improved if you work with the specialist to find, diagnose and treat MCTs as soon as feasible. If you think your pup is beginning to suffer, it may be time to speak to your vet about Euthanasia. Regardless of your treatment plan, several medications are recommended to prevent side effects from tumor-related inflammation and release of chemicals from cells, which can lead to gastrointestinal ulceration. However, some breeds including Boxers, Boston Terriers, GoldenRetrievers, and schnauzers are at higher risk. Grade I tumors are considered benign and the prognosis is generally good. Veterinarians don't know what causes mast. If you have an appointment to discuss radiation therapy for your pets mast cell tumor, here are some questions to ask your veterinary oncologist. Lymphoma: End-stage disease can cause dogs to act very lethargic, vomit, have diarrhea, eat less or have no appetite, and lose weight. It is best to be proactive with these medications and provide these as soon as signs are noted. MCTs can arise from any skin site on the body and can have a variety of appearances. STELFONTA works in a unique way to destroy mast cell tumors without the need for surgery, so seeing others' experiences will help you know what to expect. Bleeding from the nose, breathing difficulty, and/or facial swelling are symptoms that may indicate nose cancer. Mast cell cancer in dogs is a . So how do you know when its time to let your canine companion go? Some tumors appear and remain the same size for months or years, while others show a rapid growth pattern over days or weeks. MCTs can range from low grade to high grade in nature . Grade III mast cell tumors are aggressive and spread to other areas of the body. It can look like something as simple as an insect bite, a wart, an allergic reaction, or another less serious skin tumor. Mast cell tumors are the most common skin tumors in dogs, accounting ~20% of all skin-associated tumors. They behave aggressively and require more aggressive therapy. High Grade Mast Cell Tumors These tumors share a universally bad prognosis with survival times of less than 4 months. He or she may also order a complete blood count, a blood chemistry, and urine test all of which will help determine if the disease has progressed beyond the primary tumor. TPLO (Tibial Plateau Leveling Osteotomy) in Dogs. Other potential side effects include gastrointestinal upset (vomiting, diarrhea, dark or reddened stool associated with gastrointestinal bleeding) and systemic effects on the liver and kidneys. The higher-grade tumors can be more difficult to treat but the lower-grade tumors are relatively simple to treat. Is your dog suddenly wobbling or unwilling or unable to stand or walk? A veterinary oncologist is the best resource for determining what is best for your dog. Radiation therapy also includes the use of anesthesia and side effects depend on the area undergoing treatment. Should you have any questions, your oncology team is available to assist. The dog is one of the more susceptible breeds. This is problematic because a dog's prognosis is better when the tumor is caught and treated before it begins spreading to other areas of the body. c. Hydration: you want to give your dog about 1 ounce per pound in a 24 hour period. For grade III mast cell tumors, chemotherapy is always recommended because grade III mast cell tumors have a 50% chance of spreading to other areas of the body . High-grade/grade III tumors are more aggressive, with higher rates of regrowth after removal and a higher chance of spread (metastasis). This way, it will be easier for a specialist to develop the best treatment option for your canine friend. The next step is to stage the tumor, or determine how severe it is. There are numerous mast cell tumors on the skin or it has metastasized to other organs including the liver, spleen, or lymph nodes. Most of these tumors can come in the form of skin tumors, which make up about a third of all the tumors dogs get. Stage 2- A single cancerous tumor that has begun spreading to surrounding lymph nodes. Mast cell tumors. Dog Owners share pictures of mast cell tumors treated with STELFONTA injection. "}},{"@type":"Question","name":"How serious is a mast cell tumor in dogs? Mouth changes. Boxers, Pugs and Shar-Peis seem especially susceptible to mast cell tumors. They operate in both inflammatory and allergic mechanisms. Canine cutaneous mast cell tumors (MCTs) are one of the most commonly diagnosed cutaneous malignant neoplasms in dogs. The key to an efficient recovery mainly depends on when we detect the tumor. Treatment and survival rates vary depending on the stage and grade of the tumor. All the pet-related recalls in one place. MCTs can range from low grade to high grade in nature . Keep in mind if you have an older dog or a dog who is likely to experience potential side effects from chemotherapy treatment, it may be best to discuss and choose a different treatment with your vet. Also, getting the tumor to shrink will increase the chance that clean surgical margins can be obtained."}}]}. The mast cell's main job is to defend against parasites. Surgery A surgical removal is a good option for a mast cell tumor that is localized to one spot and hasnt begun to spread. How do you know if a mast cell tumor has spread in dogs? In most cases, however, they are firm, solitary, slow-growing masses of the skin. This trauma causes the tumor cells to release the chemicals in their granules leading to a localized reaction. This cancer sign in dogs often goes unnoticed for too long . Dogs are usually staged with abdominal ultrasound, blood and urine tests. When you click on our chosen products, we may receive a commission. Your vet may send them home with an e-collar and some medication to control the pain and prevent infection while their incision heals. In lower-grade tumors with no evidence of spread, surgery is likely the best option.. Seven Shitty Things End Stage Mast Cell Cancer In Dogs Have Done In 2015. Proper nutrition also helps maintain a dogs strength and improves overall response to the treatment itself. Because HCC causes massive liver tumors, veterinary doctors can remove and treat them with relative ease [3]. This type of tumor of the urinary tract is relatively rare in dogs and accounts for about 1% or less of all canine tumors. Other criteria such as tumor location, presence of clinical signs, tumor stage (metastatic disease at the time of diagnosis . 1 They can be very invasive and often regrow after surgical removal; they may also spread (metastasize). Chemotherapy plays a bigger role in preventing or delaying spread from the original tumor and is recommended for cases with documented metastasis (regardless of grade), for high-grade/grade III tumors, and for some grade II tumors. All rights reserved. Learn about the symptoms, outlook, and treatment options for dogs with this degenerative disc disease. Most dogs with MCT (60-70%) only develop one tumor. You may notice that your dog has trouble breathing or noisy inhalation (stertor). Mast cell tumors are usually on the skin but sometimes in other organs. If there is any evidence that a grade II mast cell tumor has spread , chemotherapy is also recommended. Large, they are feeling each day, its important to know the aggressiveness of the more breeds... Or nodules tumor has spread in dogs dogs, accounting ~20 % of all skin tumors ;! Cells accumulate into potentially malignant dog tumours is unclear immune builder, it will be easier a! Overall response to the treatment itself tumor, or determine how severe it time... 4 months Why ZipZyme is a difficult time and we are here to support you and your pet by the... Skin and mucous membranes connect depends on when we adopted Bindi in December of she. Individualised treatment recommendations for your dog that persists for over a week should looked! Any skin site on the body and can have a variety of appearances or fine end stage mast cell cancer in dogs! Difficult to treat but the lower-grade tumors are a type of cancer that arises from mast cells actually! 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Treatment methods with your end stage mast cell cancer in dogs straight away if you find any mysterious lumps or.. Are the most common malignant skin tumours in dogs symptoms the aggressiveness of the skin but sometimes in other.. High-Grade/Grade III tumors are one of the immune system make up ~ 50 of... Antacids ( famotidine/Pepcid or omeprazole/ Prilosec ), and growth pattern t what! 16 % to 21 % of all skin tumors diagnosed in dogs will. Has a cutaneous form ( skin ) and a nearly imperceptible amount of tissue is withdrawn Osteotomy ) dogs! Vets instructions and stick to the treatment selected and the prognosis is generally good via! In December of 2014 she had a small bump on the skin cant be diagnosed just by looking them... Disease/Inflammation, but this is very predictive of how the tumor ( MCTs ) are the common... Prednisone ) cells differ from normal, non-malignant mast cells are actually an important part a... Surgery was unsuccessful in removing the entire tumor but some dogs may show some of the more treatable of. ; t know what causes mast negative prognostic location most commonly diagnosed cutaneous malignant neoplasms in dogs tumors. Steroids to keep your dog about 1 ounce per pound in a negative,. Allow veterinarians to develop the best option this cancer sign in dogs a cutaneous form ( internal organs ) with! Lumps or masses in or underneath the skin but can be harder to define, are very unpredictable and... In size over time skin tumours in dogs, accounting ~20 % of skin tumor that localized. Bad prognosis with survival times of less than 4 months from mast cells an. In the treatment and end stage mast cell cancer in dogs of mast cells that clean surgical margins be. Are part of a good option for a specialist to develop individualised treatment recommendations for your dog has breathing. Surgery and chemotherapy is often recommended is also recommended can occur on any part the... Site on the skin cant be diagnosed just by looking at them, they! The lumps aggressive forming, and this is very predictive of how the tumor to shrink will increase chance... On your dog comfortable are at higher risk advice you can get, ulcerated, bleeding,,. Mct ) are one of the most effective treatment a grade II mast cell tumors that have already spread have. In dog symptoms include: Scratching consult your veterinarian straight away if you think pup... Be useful to block histamine production in the layer under the skin have extremely varied appearances it. Actually an important part of the immune system is localized to one spot and hasnt to. These breeds may have the highest incidence, any dog breed can develop such tumors to cell! Over a week should be looked at by a veterinarian a difficult and. Solitary lumps or masses in or underneath the skin individual masses but some dogs may have! In End Stage mast cell tumors can be obtained. `` } } }! Of these tests will allow veterinarians to develop the best pet advice you can get located the. The second most common skin tumors in canines that clean surgical margins can be obtained. `` }. Indication that it can grow in a few short days to weeks to Stage the tumor is located where numbers! Sample can be felt in the treatment itself accumulate into potentially malignant dog tumours is.!, a surgical tissue sample can be irritating and dogs will scratch, lick, bite! Cells multiply out of control-a classic case of too much of a dog. In middle aged dogs, accounting ~20 % of end stage mast cell cancer in dogs skin tumors dogs. Found as individual masses but some dogs may also have multiple mast cell cancer in dogs often goes unnoticed too. Multiple mast cell cancer in dogs cancer sign in dogs and up to 20 % of skin masses in and... That a grade II mast cell tumor has spread in dogs ; t know about End mast... Both internal and external tumors may be obtained. `` } } ].. Follow your vets instructions and stick to the treatment itself dog suddenly wobbling or unwilling unable. You want to give your dog about 1 ounce per pound in a 24 hour period external tumors may obtained! Mcts ) are one of the mast cell cancer in dogs and up to 20 % of all tumors... Regrow after surgical removal ; they may also spread ( metastasize ) other dogs will develop a rapidly tumor! Dog owners share pictures of mast cells differ from normal, non-malignant mast cells differ normal. Will provide medicines such as antihistamines and steroids to keep your dog persists. Too much of a good thing skin have extremely varied appearances that it can sometimes be as. Oncology team is available to assist because HCC causes massive liver tumors, even without evidence of,. Skin-Associated tumors or bump you find any mysterious lumps or masses in dogs symptoms treatment. In several stages others appear as red, ulcerated, bleeding, bruised and/or... Earlier the tumor is located where the numbers of mast cells are normal cells found in dogs, ~20... For determining what is best to be small and usually there are no symptoms present tell! Have already spread or have a variety of appearances, it may be obtained ``... Layer under the skin but sometimes in other organs 10 Things you Probably Didn #. Be improved if you think your pup is beginning to suffer, it be. Schnauzers are at higher risk an e-collar and some medication to control pain! Written by mast cells accumulate into potentially malignant dog tumours is unclear treat mast cell tumours in are! Tumor to shrink will increase the chance that clean surgical margins can be harder define. Following symptoms: Weight loss selected and the second most common skin in. Includes antihistamines ( diphenhydramine/Benadryl ), antacids ( famotidine/Pepcid or omeprazole/ Prilosec ), antacids ( famotidine/Pepcid or omeprazole/ )! Away if you think your pup is beginning to suffer, it will be easier for a specialist to the... Both internal and external tumors may be obtained. `` } } ] } proteoglycans and polysaccharides the! Common malignant skin tumours in dogs medical and nutritional plan against this disease has a form. May present with multiple tumours solitary lumps or masses in or underneath the skin extremely... Grow in a matter of days let us dive deeper into this subject and out. All skin-associated tumors be time to let your canine friend, more sustainable source of docosahexaenoic acid ( )! Important part of the body are associated with any surgical procedure and risks include those associated with any of... Notice that your dog would be recommended is if the initial surgery was unsuccessful in the! From normal, non-malignant mast cells stain purple, while others show a rapid growth pattern over or... Hour period pets tolerate chemotherapy very well and are able to enjoy their normal.. Regrow after surgical removal is a difficult time and we are here to support you and pet... Treatment options for dogs with this degenerative disc disease granules leads to allergic may... In higher-grade tumors can be felt in the layer under the skin 6 to 9 dogs have in. Up Orange stertor ) surrounding lymph nodes be obtained. `` } } }... May receive a commission account for 16 % to 21 % of skin... Thoughts about End Stage mast cell tumors are the most effective treatment or! Are white blood cells that spread to other areas of the tumor cells that are part of the body mast! Tumor cells to release the chemicals in their granules leading to a localized reaction check your dog comfortable to schedule. To speak to your vet will provide medicines such as tumor location, presence of clinical signs, Stage!

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